Magnesium – it's the mineral powerhouse behind everything from restful sleep and calm nerves to strong muscles and a healthy heart. But if you've ever tried to buy a magnesium supplement, you know it can feel like navigating a confusing maze of forms, doses, and big promises.
"Which one is best?" "Will this actually work?" "And what even is magnesium oxide?!"
Let's cut through the noise. Here at Patched Up, we're dedicated to delivering effective, no-fuss solutions. And when it comes to magnesium, that means understanding the science and choosing the correct form for the proper delivery.
The Magnesium Myth-Buster: Not All Magnesium is Created Equal
You might have seen tables breaking down different forms of magnesium, ranking them by how well your body can absorb them. This is crucial information, but it is often overlooked in the supplements aisle.
Here’s a quick snapshot of what you need to know about common magnesium forms:
| Form of Magnesium | Absorption via Gut (Oral) | Absorption via Skin (Topical) | Notes / Best Uses |
| Magnesium Citrate | ✅ High | ⚪ Limited | Highly bioavailable; often used for relaxation and mild constipation. |
| Magnesium Glycinate | ✅ Excellent | ⚪ Limited | Gentle on the stomach; good for sleep, anxiety, and muscle relaxation. |
| Magnesium Malate | ✅ Very Good | ⚪ Possible | Great for fatigue and muscle recovery. |
| Magnesium Threonate | ✅ Good (crosses blood–brain barrier) | ⚪ Possible | Best for cognitive and memory support. |
| Magnesium Chloride | ⚪ Moderate | ✅ Excellent | Excellent for transdermal use (oils, sprays, and our patches!). |
| Magnesium Sulfate (Epsom Salt) | ⚪ Poor orally | ✅ Good | Absorbable through skin in baths; used for muscle relaxation. |
| Magnesium Oxide | 🚫 Low | ⚪ Minimal | Poorly absorbed orally; mainly used as a laxative, not a true supplement. |
This table is a simplified guide. Always consult a healthcare professional for specific advice.
A Simple Pharmacy Rule for (Oral) Supplements
When you're looking at a bottle of magnesium pills, the most critical thing to do is ignore the significant number on the front and read the "Active Ingredients" list on the back.
Here’s a simple rule of thumb:
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Look for forms ending in "-ate" or "chelate". These are your "active" and bioavailable forms that your body can actually use.
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Glycinate
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Citrate
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Malate
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Orotate
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Amino Acid Chelate
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Avoid forms ending in "-ide" or "-onate". These are generally the poorly absorbed, cheaper forms.
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Oxide
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Hydroxide
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Carbonate
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You'll quickly notice that many popular, high-dose tablets are made mainly of Magnesium Oxide. This means that while the label is legally "active," it's not biologically active, and most of that magnesium will pass right through you. This leads us to the big problem... your gut.
The Problem with Oral Magnesium
For many, oral magnesium—even the good "-ate" forms—can cause issues like:
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Digestive Upset: Diarrhoea, stomach cramps, or nausea.
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Low Absorption: Especially with poorly bioavailable forms like Oxide.
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Inconvenience: Remembering to take multiple pills every day.
This is where transdermal magnesium (absorption through the skin) comes in. But first, let's look at why getting this mineral is so critical.
The Physiology of Relief: What Magnesium Actually Does in Your Body
Magnesium isn't just a "nice-to-have" mineral; it's a fundamental biological spark plug. It's involved in over 300 essential enzyme reactions, and it's often called the "master mineral" because, without it, your body can't function optimally.
Its most famous role? It is the excellent "off" switch.
1. For Your Muscles: The "On/Off" Switch for Contraction
This is the most direct way to understand magnesium's power against cramps, tightness, and spasms.
Think of your muscle cells as having a microscopic "on/off" switch.
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Calcium is the "ON" Switch: When your brain sends a signal, calcium floods into your muscle cells. This influx of calcium causes the muscle fibres to lock together and contract.
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Magnesium is the "OFF" Switch: For that muscle to relax, your body needs magnesium. Magnesium's job is to actively push the calcium out of the cell, allowing the muscle fibres to unlock and release.
What happens when you're low on magnesium? Your "off" switch is broken.
Calcium floods in, but there isn't enough magnesium to push it back out. The muscle cell stays contracted, and you feel it as a painful cramp, a persistent twitch (like an eyelid), or a chronic, unyielding tightness (like in your neck and shoulders).
By supplying magnesium, you are directly restoring the body's ability to "turn off" the contraction, allowing muscles to return to their natural, relaxed state.
2. For Your Nerves & Mind: The "Brake" on Your Nervous System
Your brain and nervous system work on a similar balance of "excite" and "calm" signals. Magnesium is the body's primary "calm" signal.
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It boosts GABA: Magnesium binds to and stimulates GABA receptors in your brain. GABA is your central inhibitory ("chill out") neurotransmitter. It's the signal that tells your brain to slow down, quiet racing thoughts, and promote a feeling of peace.
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It Blocks "Stress" Signals: It also sits in the "gate" of another receptor (the NMDA receptor), preventing excitatory "stress" neurotransmitters (like glutamate) from over-stimulating your brain cells.
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It Regulates Stress Hormones: Magnesium helps regulate your body's entire stress-response system (the HPA axis), allowing to control the release of the stress hormones cortisol and adrenaline.
When you have enough magnesium, your nervous system is balanced. You feel calmer, you're less reactive to stress, and your brain can transition into a deep, restorative sleep state more easily.
3. For Your Energy: The Battery Pack for Your Cells
Ironically, a "calming" mineral is also essential for energy, but it's true. Your body's primary energy currency is ATP - for this to be stable and usable, it must be bound to a magnesium ion (forming Mg-ATP).
No magnesium means no usable energy. This is why a deficiency so often manifests as profound fatigue, weakness, and exhaustion.
The Patched Up Solution: Why We Use Magnesium Chloride
So, the need for magnesium is clear. The problem, as we've seen, is getting it into the body without aggravating the gut.
This brings us back to our simple pharmacy rule and its one, crucial exception: Magnesium Chloride.
Remember our rule to "avoid -ide" forms for swallowing? Well, Magnesium Chloride is the key exception because it is not an oral supplement. As our table shows, while it's not great for eating, Magnesium Chloride is Excellent (✅) for topical delivery. It's the most respected and scientifically studied form for absorption through the skin.
At Patched Up, we've chosen Magnesium Chloride for our Smart Magnesium Patches for this straightforward, science-backed reason: it's the best form for topical delivery.
Your skin is a fantastic organ that readily absorbs Magnesium Chloride. This means:
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Direct Absorption: The magnesium bypasses your digestive system entirely, avoiding any potential gut upset.
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Highly Bioavailable: You're getting a form that your body can effectively absorb and utilise when applied to the skin, ready to go to work in your muscles and nerves.
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Convenient & Sustained Release: No messy oils, no forgotten pills. Just apply a patch and let it work slowly and steadily for hours.
**Say goodbye to the magnesium maze and hello to effortless relief.